Change-N1 peaking 90–180 ms after changes in a sound feature of a continuous sound is clearly attenuated by a preceding change stimulus (called a "prepulse"). Here, we investigated the effects of a preceding decrease in sound pressure on the degree of inhibition of the subsequent Change-N1 amplitude. Using 100-Hz click train sounds, we obtained Change-N1s from 11 healthy volunteers. The two types of test stimuli were an abrupt 10-dB increase from the baseline (70 dB) and the insertion of a 0.45-ms inter-aural time difference in the middle of the sound. Three consecutive clicks at 30, 40, and 50 ms before the change onset that was used as a prepulse were weaker than the background by 5 or 10 dB. The Change-N1 elicited by the two test stimuli was attenuated more strongly by the weaker prepulse, which was not congruent with the theory that the inhibition of the subsequent sensory/sensory-motor processing depends on the sound pressure level of a prepulse. These results suggest that a change in any type of sound feature elicits a change-related response that is inhibited by any type of preceding change stimulus, which reflects auto-inhibition of the change-responding circuit.

Change-N1 在连续声音的声音特征变化后 90-180 ms 达到峰值，明显被先前的变化刺激（称为“前脉冲”）减弱。在这里，我们研究了先前声压降低对后续 Change-N1 振幅抑制程度的影响。使用 100 Hz 的咔嗒声，我们从 11 名健康志愿者那里获得了 Change-N1s。两种类型的测试刺激是从基线 (70 dB) 突然增加 10 分贝和在声音中间插入 0.45 毫秒的耳间时间差。在用作前脉冲的变化开始前 30、40 和 50 毫秒连续三次点击比背景弱 5 或 10 dB。两个测试刺激引起的 Change-N1 被较弱的前脉冲更强烈地衰减，这与随后的感觉/感觉运动处理的抑制取决于前脉冲的声压级的理论不一致。这些结果表明，任何类型的声音特征的变化都会引起与变化相关的响应，该响应被任何类型的先前变化刺激所抑制，这反映了变化响应电路的自动抑制。