White-rot basidiomycetic fungi have gained a lot of scientific attention in recent years owing to their ability to produce cellulase enzymes that are of great importance in numerous industrial applications. This has seen a rise in number of studies seeking to comprehend both physical and molecular mechanisms that regulate the production of cellulase enzymes in these fungi. Cellulase has several applications in production of food and beverages, biofuel, biological detergents, pharmaceuticals, and deinking in paper and pulp industry. Enhanced understanding of genetic mechanisms that regulate cellulase production would have utility for optimal cellulase production in white-rot basidiomycetes using biotechnology approaches. Carbon catabolite repression and various transcriptional factors such as XlnR, Cre, Clr, Ace, and gna1 control expression of genes encoding cellobiohydrolase (CBH), endoglucanase (EGL) and β-glucosidase (BGL). In this review, we have consolidated and summarised some of recent findings on genetic regulation of cellulase with an aim of highlighting the general regulatory mechanisms that underlie cellulase expressions in white-rot fungi. This review further outlines some of important transcription factors that regulate cellulase genes, and key research gaps that may need to be addressed by future research.

近年来，白腐担子菌真菌由于其产生纤维素酶的能力而在科学上引起了广泛关注，纤维素酶在许多工业应用中都非常重要。越来越多的研究试图了解调节这些真菌中纤维素酶产生的物理和分子机制。纤维素酶在食品和饮料，生物燃料，生物洗涤剂，制药以及造纸和纸浆工业的脱墨中具有多种应用。使用生物技术方法，对调节纤维素酶产生的遗传机制的增强理解将对白腐烂担子菌的最佳纤维素酶产生有用。碳分解代谢物阻遏和各种转录因子，例如XlnR，Cre，Clr，Ace，gna1和gna1控制编码纤维二糖水解酶（CBH），内切葡聚糖酶（EGL）和β-葡萄糖苷酶（BGL）的基因的表达。在这篇综述中，我们巩固和总结了有关纤维素酶遗传调控的一些最新发现，目的是强调构成白腐真菌中纤维素酶表达基础的一般调控机制。这篇综述进一步概述了调节纤维素酶基因的一些重要转录因子，以及未来研究可能需要解决的关键研究空白。