Magnetic Resonance Materials in Physics Biology and Medicine ( IF 2.3 ) Pub Date : 2020-07-21 , DOI: 10.1007/s10334-020-00866-0 Markus Sack 1, 2 , Lei Zheng 2, 3 , Natalia Gass 1, 2 , Gabriele Ende 1 , Alexander Sartorius 2, 4 , Wolfgang Weber-Fahr 1, 2
Objective
Brain atlases are important research tools enabling researchers to focus their investigations on specific anatomically defined brain regions and are used in many MRI applications, e.g. in fMRI, morphometry, whole brain spectroscopy, et cetera. Despite their extensive use and numerous versions they usually consist of predefined rigid brain regions with a given level of detail often degrading them to a non-ideal tool in special research topics.
Result
To overcome this intrinsic weakness we present a graphical user interface application which allows researchers to easily create mouse brain atlases with an adjustable user-defined level of detail and coverage to match specific research questions.
中文翻译:
为小鼠大脑成像创建可调整解剖图谱的交互式工具。
客观的
脑图谱是重要的研究工具,使研究人员能够将研究重点放在特定的解剖学定义的大脑区域,并用于许多 MRI 应用,例如 fMRI、形态测量学、全脑光谱学等。尽管它们被广泛使用且版本众多,但它们通常由具有给定细节水平的预定义刚性大脑区域组成,这通常将它们降级为特殊研究课题中的非理想工具。
结果
为了克服这个内在的弱点,我们提出了一个图形用户界面应用程序,它允许研究人员轻松创建鼠标大脑图谱,其具有可调整的用户定义的详细程度和覆盖范围,以匹配特定的研究问题。