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1H, 13C and 15N resonance assignments for the microtubule-binding domain of the kinetoplastid kinetochore protein KKT4 from Trypanosoma brucei.
Biomolecular NMR Assignments ( IF 0.9 ) Pub Date : 2020-07-21 , DOI: 10.1007/s12104-020-09968-1
Patryk Ludzia 1 , Bungo Akiyoshi 1 , Christina Redfield 1
Affiliation  

KKT4 is a kinetoplastid-specific microtubule-binding kinetochore protein that lacks significant similarity to any known kinetochore or microtubule-binding proteins. Here we present the 1H, 13C and 15N resonance assignments for several fragments from the microtubule-binding domain of KKT4 (KKT4115–343) from Trypanosoma brucei. These assignments provide the starting point for detailed investigations of the structure, dynamics and interactions of the microtubule-binding region of KKT4.

中文翻译:

来自布氏锥虫的动质体动粒蛋白 KKT4 的微管结合域的 1H、13C 和 15N 共振分配。

KKT4 是一种动质体特异性微管结合动粒蛋白,与任何已知的动粒或微管结合蛋白缺乏显着相似性。在这里,我们展示了来自布氏锥虫的 KKT4 (KKT4 115-343 )微管结合域的几个片段的1 H、13 C 和15 N 共振分配。这些分配为详细研究 KKT4 微管结合区的结构、动力学和相互作用提供了起点。
更新日期:2020-07-21
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