Tailor-made reverse transcriptases are used in molecular biology and synthetic genetics. However, re-engineering these enzymes to work with non-natural nucleic acids is difficult and requires powerful directed evolution strategies. Now, an adaptable selection approach has been demonstrated for the evolution of new reverse transcriptases.

中文翻译：

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扩展反转录工具箱。

量身定制的逆转录酶用于分子生物学和合成遗传学。然而，对这些酶进行改造以使其与非天然核酸结合是困难的，并且需要强有力的定向进化策略。现在，已经证明了一种适应性选择方法用于新逆转录酶的进化。