Response inhibition relies on both proactive and reactive mechanisms that exert a synergic control on goal-directed actions. It is typically evaluated by the go/no-go (GNG) and the stop signal task (SST) with response recording based on the key-press method. However, the analysis of discrete variables (i.e., present or absent responses) registered by key-press could be insufficient to capture dynamic aspects of inhibitory control. Trying to overcome this limitation, in the present study we used a mouse tracking procedure to characterize movement profiles related to proactive and reactive inhibition. A total of fifty-three participants performed a cued GNG and an SST. The cued GNG mainly involves proactive control whereas the reactive component is mainly engaged in the SST. We evaluated the velocity profile from mouse trajectories both for responses obtained in the Go conditions and for inhibitory failures. Movements were classified as one-shot when no corrections were observed. Multi-peaked velocity profiles were classified as non-one-shot. A higher proportion of one-shot movements was found in the SST compared to the cued GNG when subjects failed to inhibit responses. This result suggests that proactive control may be responsible for unsmooth profiles in inhibition failures, supporting a differentiation between these tasks.

中文翻译：

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鼠标跟踪以探索执行/不执行和停止信号任务中的运动抑制过程。

抑制反应依赖于主动和反应机制，这些机制对目标导向的行为施加协同控制。它通常由通过/不通过（GNG）和停止信号任务（SST）进行评估，并具有基于按键方法的响应记录。但是，通过按键记录的离散变量（即，存在或不存在的响应）的分析可能不足以捕获抑制控制的动态方面。为了克服这一限制，在本研究中，我们使用了鼠标跟踪程序来表征与主动和反应性抑制相关的运动曲线。共有53位参与者进行了提示GNG和SST。提示的GNG主要涉及主动控制，而反应成分主要参与SST。我们评估了在Go条件下获得的响应和抑制性失败的小鼠轨迹的速度曲线。如果未观察到矫正，则将运动归为一发。多峰速度曲线被分类为非单发。当受试者未能抑制反应时，与提示的GNG相比，在SST中发现了更高比例的单发运动。该结果表明，主动控制可能是抑制失败中不平滑的原因，支持了这些任务之间的区分。当受试者未能抑制反应时，与提示的GNG相比，在SST中发现了更高比例的单发运动。该结果表明，主动控制可能是抑制失败中不平滑的原因，支持了这些任务之间的区分。当受试者未能抑制反应时，与提示的GNG相比，在SST中发现较高的单发运动比例。该结果表明，主动控制可能是抑制失败中不平滑的原因，支持了这些任务之间的区分。