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New core configuration for the fabrication of 125I radioactive sources for cancer treatment.
Applied Radiation and Isotopes ( IF 1.6 ) Pub Date : 2020-07-20 , DOI: 10.1016/j.apradiso.2020.109307
Carla Daruich de Souza 1 , Carlos Alberto Zeituni 1 , Anselmo Feher 1 , João Augusto Moura 1 , Osvaldo Luiz da Costa 1 , Lucas Verdi Angelocci 1 , Maria Elisa C M Rostelato 1
Affiliation  

In order to provide prostate brachytherapy treatment for more Brazilian men, IPEN is building a laboratory for the manufacture of radioactive sources. The new methodology for the production of iodine-125 seeds with yield 71.7% ± 5.3%. Points of importance were evaluated/discussed: photo-sensibility, reaction vial type, the substitution for iodine-131, pH, and solution volume. The surface was analyzed by FTIR and EDS. At the end, a Monte Carlo-MCNP6 simulation was performed to evaluate the TG-43 parameters.



中文翻译:

用于制造用于癌症治疗的 125I 放射源的新核心配置。

为了为更多的巴西男性提供前列腺近距离放射治疗,IPEN 正在建设一个制造放射源的实验室。生产碘 125 种子的新方法,产量为 71.7% ± 5.3%。评估/讨论了重要点:光敏性、反应瓶类型、碘 131 的替代、pH 值和溶液体积。通过FTIR和EDS分析表面。最后,进行了蒙特卡罗-MCNP6 模拟以评估 TG-43 参数。

更新日期:2020-07-20
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