Nanotechnology has made great contributions in the development of materials with potential application in different areas, especially in the pharmaceutical sector, where nano-systems are being intensely studied for controlled drug release. These innovative systems are composed of structures such as nanoparticles, nanoemulsions, and cyclodextrins, with the aim of promoting enhanced bioavailability of bioactive molecules. Among these nanocarriers, vesicles such as liposomes and polymersomes are considered to be promising alternatives in delivering hydrophilic and lipophilic drugs. They have different classifications according to their composition, among which are hybrid vesicles, which unlike liposomes are composed of both lipids and polymers. These vesicular systems stand out for combining the advantages of both components, overcoming the limitations of traditional systems imposed by low stability and premature release of the encapsulated active substance. The polymers applied in hybrid vesicles can make up the membrane structure itself or be employed to coat preformed vesicles. Due to the relevance of these systems, this work covers their characteristics and summarizes recent articles about them in the literature.

中文翻译：

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基于脂类和聚合物的混合囊泡纳米系统，用于治疗，治疗学和化妆品。

纳米技术为材料的开发做出了巨大贡献，这些材料在不同领域具有潜在的应用前景，尤其是在制药领域，人们正在对纳米系统进行可控药物释放的研究。这些创新的系统由纳米粒子，纳米乳剂和环糊精等结构组成，目的是提高生物活性分子的生物利用度。在这些纳米载体中，诸如脂质体和聚合物体之类的囊泡被认为是递送亲水性和亲脂性药物的有希望的替代物。它们根据其组成具有不同的分类，其中杂种囊泡与脂质体不同，杂种囊泡由脂质和聚合物组成。这些囊泡系统在结合两个组件的优势方面脱颖而出，克服了传统系统因封装的活性物质稳定性低和过早释放而受到的限制。应用于混合囊泡的聚合物可自身构成膜结构，或用于涂覆预制的囊泡。由于这些系统的相关性，这项工作涵盖了它们的特征，并在文献中总结了有关它们的最新文章。