Some new hybrid 2-aryl-4-(1-phenyl-3-(p-tolyl)-1H-pyrazol-4-yl)-2,3-dihydro-1H-benzo[b][1,4]diazepines have beensynthesised which possessed the pyrazole and benzodiazepine heterocycles 2a-t. Antimicrobial evaluation of the synthesizedcompounds have been carried out against different strains of bacteria like E. coli, P. aeruginosa, S. aureus and S. pyogenesand fungal strains like C. albicans, A. niger and A. clavatus using serial dilution method. The newly synthesized compounds2i, 2j, 2k, 2l, 2m, 2q and 2t have shown significant activity against the above mentioned strains. The reported compounds inthe present paper are supported by IR, ¹H and ¹³C NMR, and LC-MS spectral analysis.

一些新的杂种2-芳基-4-（1-苯基-3-（对甲苯基）-1H-吡唑-4-基）-2,3-二氢-1H-苯并[b] [1,4]二氮杂合成了吡唑和苯并二氮杂杂环2a-t。已使用连续稀释法对合成的化合物针对不同的细菌菌株（如大肠杆菌，铜绿假单胞菌，金黄色葡萄球菌和化脓性链球菌）以及真菌菌株（如白色念珠菌，黑曲霉和曲霉）进行了抗菌评估。新合成的化合物2i，2j，2k，2l，2m，2q和2t对上述菌株表现出显着的活性。本文报道的化合物得到IR，¹ H和¹³ C NMR以及LC-MS光谱分析的支持。