Objective

Evaluate the occurrence of sarcopenia and determinant factors in individuals with Parkinson’s disease (PD) in a city in northeastern Brazil.

Methods

Case series with 77 men and women (adults and older adults) with PD. The risk of sarcopenia was determined using the SARC-F and SARC-CalF screening tools. The diagnosis of sarcopenia was based on the new consensus published by the European Working Group on Sarcopenia in Older People (EWGSOP2). Sarcopenic obesity was diagnosed based on the criteria proposed by Stenholm. Disease stage and severity were determined using the Hoehn and Yahr scale and the Unified Parkinson Disease Rating Scale, respectively.

Results

The prevalence of sarcopenia was 19.5% and was associated with age, poor performance on activities of daily living and poor nutritional status. No significant association was found between the SARC-F score and the diagnosis of sarcopenia. The main factors that determined the variation in the parameters for the diagnosis of sarcopenia in the present sample were age, disease severity, body weight, and SARCF score.

Conclusion

Despite the low prevalence in the present study, sarcopenia progresses with the worsening of the nutritional status and functional capacity of individuals with PD. Further studies are needed on the factors involved in the genesis of sarcopenia. The SARC-F questionnaire is related to parameters for the diagnosis and severity of sarcopenia as well as the severity of PD.

中文翻译：

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帕金森氏病患者肌肉减少症的决定因素。

目的

评估巴西东北部城市患有帕金森氏病（PD）的人的肌肉减少症和决定因素的发生情况。

方法

案例系列，有77名患有PD的男性和女性（成人和老年人）。使用SARC-F和SARC-CalF筛查工具确定了肌肉减少症的风险。肌肉减少症的诊断是基于欧洲老年人肌肉减少症工作组（EWGSOP2）发布的新共识。根据Stenholm提出的标准诊断为少肌肥胖。分别使用Hoehn和Yahr量表和统一帕金森氏病评分量表确定疾病的阶段和严重程度。

结果

肌肉减少症的患病率为19.5％，与年龄，生活活动表现差和营养状况差有关。在SARC-F评分与肌肉减少症的诊断之间未发现显着相关性。决定本样本中少肌症诊断参数变化的主要因素是年龄，疾病严重程度，体重和SARCF评分。

结论

尽管本研究的患病率较低，但肌肉减少症会随着PD患者营养状况和功能能力的恶化而发展。关于肌肉减少症发生的相关因素还需要进一步研究。SARC-F调查表与肌肉减少症的诊断和严重程度以及PD的严重程度有关。