Abstract

The introduction of certain structures or functional groups on benzothiazole and its derivatives containing a benzene ring and a thiazole ring can be used to construct benzothiazole fluorescent probes. Based on the mechanism of photoinduced electron transfer, excited-state intramolecular proton transfer (ESIPT), intramolecular charge transfer, aggregation-induced emission, the obtained fluorescent probes can specifically interact with the analyte, thereby changing their luminescence characteristics to achieve the detection of the analyte. Benzothiazole fluorescent probes can be applied to the detection of substances, the analysis of harmful substances and cell imaging. In this paper, the research situation of benzothiazole fluorescent probes in the past 5 years is reviewed, and it is mainly divided into metal ions, anions, small molecules and biological macromolecules according to the types of analytes. In the conclusion, the current challenges and further applications of benzothiazole fluorescent probes are analyzed.

Graphic abstract

Application of detection and analysis of benzothiazole fluorescent probes.

中文翻译：

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苯并噻唑用作分析物检测的荧光探针

摘要

苯并噻唑及其包含苯环和噻唑环的衍生物上的某些结构或官能团的引入可用于构建苯并噻唑荧光探针。基于光致电子转移，激发态分子内质子转移（ESIPT），分子内电荷转移，聚集诱导发射的机理，获得的荧光探针可以与分析物特异性相互作用，从而改变其发光特性以实现对分析物。苯并噻唑荧光探针可用于物质检测，有害物质分析和细胞成像。综述了近5年来苯并噻唑荧光探针的研究现状，主要分为金属离子，阴离子，小分子和生物大分子根据分析物的类型而定。总之，分析了苯并噻唑荧光探针的当前挑战和进一步的应用。

图形摘要

苯并噻唑荧光探针的检测和分析应用。