Polyphasic taxonomic analysis was performed on a novel bacterium, designated UR159^T, isolated in 2016 from human blood of a septic patient hospitalized in France. Preliminary 16S rRNA gene sequence-based phylogenetic analysis indicated that strain UR159^T belonged to the family Flavobacteriaceae, forming a distinct phyletic line distantly related (<94% sequence similarity) to known species of the family. Further phenotypic, chemotaxonomic and genomic analyses were performed. Cells were non-motile, oxidase-negative, catalase-positive Gram-negative rods. It was strictly aerobic yielding yellow-pigmented colonies, and was metabolically rather inert. Major fatty acids were iso-branched fatty acids, predominantly iso-C_15:0 (55.5%) and iso-C_17:1ω9c (8.8%). Whole genome sequencing revealed a 2.3-Mbp genome encoding a total of 2262 putative genes with a genomic DNA G + C content at 37.6 mol%. The average nucleotide identity (ANI) and in silico DNA-DNA hybridization (isDDH) values between strain UR159^T and the most closely related members of the Flavobacteriaceae family were <75% and <39%, respectively, much below the established cut-offs for ANI (<95–96%) and isDDH (<70%) for species and genus delineation. Average Amino Acid Identity (AAI) percentages were also estimated and were lower than 65% (cut-off proposed for genus delineation for uncultivated prokaryotes) in all cases, except for F. marinum that was just at the limit (65.1%). Based on these findings, we propose it as a new genus and species, Avrilella dinanensis gen. nov., sp. nov. (type strain UR159^T = CIP 111616^T = DSM 105483^T).

2016年从法国住院的脓毒症患者的人血中分离出了一种新型细菌，命名为UR159 ^T，进行了多相分类学分析。初步的基于16S rRNA基因序列的系统发育分析表明，菌株UR159 ^T属于黄杆菌科，形成了与该家族已知物种远缘相关（<94％序列相似性）的独特系系。进行了进一步的表型，化学分类和基因组分析。细胞是不活动的，氧化酶阴性，过氧化氢酶阳性的革兰氏阴性棒。它是严格有氧的，产生黄色色素的菌落，并且在代谢上是惰性的。主要脂肪酸为异支链脂肪酸，主要为iso-C _15：0（55.5％）和异-C _17：1 ω 9 Ç（8.8％）。全基因组测序揭示了一个2.3 Mbp的基因组，该基因组总共编码2262个推定基因，其基因组DNA G + C含量为37.6 mol％。菌株UR159 ^T与黄杆菌科家族中最亲近的成员之间的平均核苷酸同一性（ANI）和计算机DNA-DNA杂交（isDDH）值分别小于75％和39％，远低于既定的临界值对于物种和属的划分，ANI（<95–96％）和isDDH（<70％）。还估计了所有情况下的平均氨基酸同一性（AAI）百分比，这些百分比均低于65％（对于未培养的原核生物，建议的界线为界线），但海藻除外。刚刚达到极限（65.1％）。基于这些发现，我们建议将其作为一种新的属和种，即Avrilella dinanensis属。十一月，sp。十一月 （类型UR159 ^T  = CIP 111616 ^T  = DSM 105483 ^T）。