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Recent advances in nitro-involved radical reactions
Organic Chemistry Frontiers ( IF 5.4 ) Pub Date : 2020-07-17 , DOI: 10.1039/d0qo00563k
Jiapian Huang 1, 2, 3, 4 , Feng Ding 1, 2, 3, 4 , Pornchai Rojsitthisak 5, 6, 7, 8, 9 , Fu-Sheng He 1, 2, 3, 4 , Jie Wu 1, 2, 3, 4, 10
Affiliation  

Nitro-containing compounds are important structural moieties in drugs, natural products, and small molecule therapeutics, and are widely used in a variety of organic transformations. During the past decades, these compounds have received considerable attention from the synthetic chemistry community, since they have been successfully applied in the preparation of amines, oximes, alkenes, nitrones and alcohols through the radical-initiated pathway. Additionally, significant progress in the chemistry of nitro radicals has been witnessed, providing efficient and rapid access to nitro-containing compounds as well as isoxazoline derivatives. Recent advances in the radical reactions involving the nitro group and various transformations have been summarized in this review.

中文翻译:

硝基自由基反应的最新进展

含氮化合物是药物,天然产物和小分子疗法中的重要结构部分,并广泛用于各种有机转化中。在过去的几十年中,这些化合物已成功地通过自由基引发的途径用于制备胺,肟,烯烃,硝酮和醇,因此受到了合成化学界的广泛关注。另外,已经见证了硝基自由基化学的重大进展,提供了高效,快速地获得含硝基化合物以及异恶唑啉衍生物的途径。这篇综述总结了涉及硝基的自由基反应和各种转化的最新进展。
更新日期:2020-09-16
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