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Administering dexamethasone to prepartum sows: Effects on sow and piglet performance
Livestock Science ( IF 1.8 ) Pub Date : 2020-07-17 , DOI: 10.1016/j.livsci.2020.104171
Sophia A. Ward , Roy N. Kirkwood , Kate J. Plush

There is a considerable gap in available literature regarding the use of prepartum steroidal anti-inflammatory drugs (SAIDs) despite their ability to provide a targeted response to pain. The aim of this investigation was to determine whether prepartum administration of dexamethasone to sows would influence farrowing and/or lactation processes, with the prediction that it would affect both sow and piglet performance. Sows were induced to farrow on day 113 of gestation (2 days before their 115 day due date) and were treated with dexamethasone concurrent with induction (DexInd; n = 20), 24 h after induction (Dex24; n = 20), at induction and 24 h later (Dextwice; n = 19) or no steroid treatment (Control; n = 20). Treating with dexamethasone at induction reduced birth and weaning weights (P = 0.001), plasma total protein concentrations (P = 0.001), and colostrum intake of piglets of multiparous sows (P = 0.006). Treating with dexamethasone 24 h after induction did not adversely affect piglet weights or plasma total protein and improved average daily gain in piglets (P = 0.001). Although no differences were observed for farrowing duration or piglet survival (P > 0.05), further investigation is required using higher parity sows to qualify whether glucocorticoids can improve farrowing performance.



中文翻译:

地塞米松对产前母猪的管理:对母猪和仔猪生产性能的影响

尽管有提供针对疼痛的靶向反应的能力,但有关使用产前甾体抗炎药(SAID)的现有文献仍有相当大的差距。这项研究的目的是确定对母猪进行地塞米松的产前管理是否会影响分娩和/或泌乳过程,并预测会影响母猪和仔猪的生产性能。母猪在妊娠第113天(到期日115天前2天)被 诱导分娩 ,并在诱导后24小时(Dex24;n = 20)同时接受地塞米松和诱导(DexInd;n = 20)治疗。24小时后(Dextwice;n  = 19)或不进行类固醇治疗(对照组;n = 20)。地塞米松诱导诱导治疗可降低出生和断奶体重(P  = 0.001),血浆总蛋白浓度(P  = 0.001)和多头母猪仔猪的初乳摄入量(P  = 0.006)。诱导后24小时用地塞米松治疗不会对仔猪体重或血浆总蛋白产生不利影响,并改善了仔猪的平均日增重(P  = 0.001)。尽管未观察到分娩持续时间或仔猪存活率存在差异(P  > 0.05),但仍需要使用更高胎次的母猪进行进一步调查,以确认糖皮质激素是否可以改善分娩性能。

更新日期:2020-07-17
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