The occurrence of selected pharmaceuticals (trimethoprim, sulfamethoxazole, chloramphenicol, bezafibrate, ceftriaxone, and naproxen) in two west-flowing tropical rivers (Swarna and Nethravati) of southwestern India is reported for the first time. Water samples were collected during the monsoon and post-monsoon seasons from river water end members and further downstream up to their confluence with the adjacent Arabian Sea. Samples were analyzed using HPLC–MS/MS. Results revealed that there were no significant seasonal variations in concentrations of target analytes in both the rivers. Of the total number of samples analyzed (n = 24), trimethoprim was detected in 100% of the samples, whereas sulfamethoxazole (SMX), chloramphenicol (CAP), ceftriaxone (CTX), and naproxen (NPX) were detected in between 91 and 58% of the samples. Bezafibrate (BZF) was not detected in the samples. Nethravathi river showed higher concentrations of pharmaceuticals than the Swarna river which may be attributed to comparatively larger human population in the basin. Possible impacts of PPCPs on aquatic life offer further scope for study.

中文翻译：

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关于印度西南部两条热带河流的药品和个人护理产品的第一份报告。

首次报道了印度西南部两条向西流出的热带河流（Swarna和Nethravati）中出现了某些药物（甲氧苄啶，磺胺甲恶唑，氯霉素，苯扎贝特，头孢曲松和萘普生）的发生。在季风季节和季风后季节期间，从河水末端成员以及下游进一步收集水样，直到它们与相邻的阿拉伯海汇合为止。使用HPLC-MS / MS分析样品。结果表明，两条河流中目标分析物的浓度均无明显的季节性变化。在分析的样品总数中（n = 24），则在100％的样品中检出了甲氧苄啶，而在91％至58％的样品中检出了磺胺甲恶唑（SMX），氯霉素（CAP），头孢曲松（CTX）和萘普生（NPX）。在样品中未检测到苯扎贝特（BZF）。Nethravathi河的药物浓度高于Swarna河，这可能归因于流域的人口相对较多。PPCP对水生生物的可能影响提供了进一步的研究范围。