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Circulating vaccine-derived poliovirus: a menace to the end game of polio eradication.
Globalization and Health ( IF 10.8 ) Pub Date : 2020-07-16 , DOI: 10.1186/s12992-020-00594-z
Long Chiau Ming 1 , Zahid Hussain 2 , Siang Fei Yeoh 3 , David Koh 1, 4 , Kah Seng Lee 5
Affiliation  

The World Health Organisation Western Pacific Region countries were declared free of polio in 2000 until a polio outbreak involving 305 cases occurred in Indonesia in 2006. It was not until 2014 that the World Health Organisation South East Asia region was officially declared polio-free again. However, in February 2019, the Global Polio Eradication Initiative announced a new circulating vaccine-derived poliovirus outbreak in the Papua province of Indonesia. To make matter worse, the outbreak responses were tardy and led to transmission among migrating communities to other cities. The pressing regional issues of polio outbreak caused by circulating vaccine-derived poliovirus and use of oral polio vaccine have not been well presented. Our letter highlighted the suboptimal outbreak responses as well as the necessity of cross-border vaccination to curb continued poliovirus transmission.

中文翻译:

循环疫苗衍生的脊髓灰质炎病毒:消灭脊髓灰质炎最终局面的威胁。

世界卫生组织西太平洋区域国家于2000年宣布无小儿麻痹症,直到2006年印度尼西亚发生涉及305例小儿麻痹症的暴发。直到2014年,世界卫生组织东南亚区域才再次正式宣布无小儿麻痹症。然而,在2019年2月,全球根除脊髓灰质炎行动宣布了在印度尼西亚巴布亚省发生的新的循环疫苗源性脊髓灰质炎病毒爆发。更糟的是,暴发反应迟钝,导致移民社区之间传播到其他城市。由循环疫苗衍生的脊髓灰质炎病毒引起的脊髓灰质炎暴发的紧迫区域问题和口服脊髓灰质炎疫苗的使用尚未得到很好的介绍。
更新日期:2020-07-16
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