Complete reaction pathway of prebiotic reactions for formation of the purine nucleobases adenine, hypoxanthine, guanine, isoguanine, 2,6‐diaminopurine, and xanthine from pure formamide are presented. All reactants (hydrogen cyanide, ammonia, water, formic acid, urea) and catalysts (formamide and formimidic acid) needed in the self‐catalyzed reactions are available from a starting compound, formamide. The required raw materials are obtained by partial decomposition of formamide.

中文翻译：

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益生元反应的自催化机制：从甲酰胺到嘌呤碱

给出了由纯甲酰胺形成嘌呤核苷腺嘌呤，次黄嘌呤，鸟嘌呤，异鸟嘌呤，2,6-二氨基嘌呤和黄嘌呤的益生元反应的完整反应途径。自催化反应所需的所有反应物（氰化氢，氨，水，甲酸，尿素）和催化剂（甲酰胺和亚甲二酸）都可从原料甲酰胺中获得。所需原料通过甲酰胺的部分分解获得。