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High altitude reduces infection rate of COVID-19 but not case-fatality rate.
Respiratory Physiology & Neurobiology ( IF 2.3 ) Pub Date : 2020-07-15 , DOI: 10.1016/j.resp.2020.103494
Jose Segovia-Juarez 1 , Jesús M Castagnetto 2 , Gustavo F Gonzales 3
Affiliation  

Coronavirus disease 19 (COVID-19) is a pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). It is suggested that life at high altitude may reduce COVID-19 infections and case-fatality rates (cases/deaths). We study data from Peru COVID-19 pandemics, which first case was recorded on March 6th, 2020. By June 13, 2020 there were 6498 deaths, and 224,132 SARS-CoV-2 positives. Using data from 185 capitals of provinces with altitudes ranging from 3 to 4342 m, we confirm previous reports that infection with COVID-19 at high altitude is reduced. However, case-fatality rate is not dependent of altitude. We have also presented first evidence that female protection towards death by COVID-19 is reduced as altitude of residence increases.



中文翻译:

高海拔会降低 COVID-19 的感染率,但不会降低病死率。

冠状病毒病 19 (COVID-19) 是由严重急性呼吸系统综合症冠状病毒 2 (SARS-CoV-2) 引起的大流行。建议高海拔生活可能会降低 COVID-19 感染率和病死率(病例/死亡)。我们研究了秘鲁 COVID-19 大流行的数据,第一例病例记录于 2020 年 3 月 6 日。截至 2020 年 6 月 13 日,已有 6,498 人死亡,224,132 人 SARS-CoV-2 呈阳性。利用来自海拔 3 至 4342 m 的 185 个省份首府的数据,我们证实了之前的报告,即高海拔地区的 COVID-19 感染有所减少。然而,病死率与海拔高度无关。我们还提供了第一个证据,表明随着居住海拔的升高,女性对 COVID-19 死亡的保护会降低。

更新日期:2020-07-21
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