Abstract Two novel mixed-ligand Cu(II) coordination polymers (CPs) {[Cu2(edpc)2(ga)2]·2H2O}n (1) and {[Cu(edpc)(bpdc)]·0.25(H2O)}n (2) (H2ga = glutaric acid, edpc = 9-ethyl-2,6-di-pyridin-4-yl-9H-carbazole, H2bpdc = biphenyl-4,4′-dicarboxylic acid) have been solvothermally formed through a π-conjugated carbazole-containing pyridine ligand under the presence of auxiliary ligands (H2ga for the complex 1 and H2bpdc for complex 2). Due to its good water stability of complex 2, it was applied in the photocatalytic rhodamine B (RhB), methylene blue (MB) and methyl orange (MO) degradation in unclean water, and the possible pathway of photocatalytic degradation was researched. Whether the compounds could enhance the treatment activity of the BDNF modified bone marrow mesenchymal stem cells (BMSC) against craniocerebral trauma was then evaluated. The recognition of the craniocerebral trauma mice was assessed by Morris water maze (MWM). The viability of the nerve cells in the brain was evaluated by Cell Counting Kit-8 (CCK-8). Then the enzyme-linked immuno sorbent assay (ELISA) detection was performed to detect the release content of the brain-originated neurotrophic factor and nerve promoting factor β in peripheral regions of cerebral hemorrhage. Finally, the expression levels of the complement C3 receptor on the nerve cells in the brain was also determined.

中文翻译：

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两种基于Cu（II）的配位聚合物：光催化染料降解和治疗活性结合BDNF修饰的骨髓间充质干细胞通过增加补体C3表达对颅脑外伤

摘要 两种新型混合配体 Cu(II) 配位聚合物 (CPs) {[Cu2(edpc)2(ga)2]·2H2O}n (1) 和 {[Cu(edpc)(bpdc)]·0.25(H2O) }n (2) (H2ga = 戊二酸, edpc = 9-ethyl-2,6-di-pyridin-4-yl-9H-carbazole, H2bpdc = biphenyl-4,4'-dicarbazole)在辅助配体（配合物 1 为 H2ga，配合物 2 为 H2bpdc）存在下，π 共轭的含咔唑的吡啶配体。由于配合物2具有良好的水稳定性，将其应用于不净水中光催化降解罗丹明B（RhB）、亚甲蓝（MB）和甲基橙（MO），并研究了光催化降解的可能途径。然后评估这些化合物是否可以增强 BDNF 修饰的骨髓间充质干细胞 (BMSC) 对颅脑外伤的治疗活性。颅脑外伤小鼠的识别通过莫里斯水迷宫（MWM）评估。通过细胞计数试剂盒-8 (CCK-8) 评估大脑中神经细胞的活力。然后进行酶联免疫吸附试验（ELISA）检测，检测脑出血外周区脑源性神经营养因子和神经促进因子β的释放量。最后，还测定了大脑神经细胞上补体 C3 受体的表达水平。然后进行酶联免疫吸附试验（ELISA）检测，检测脑出血外周区脑源性神经营养因子和神经促进因子β的释放量。最后，还测定了大脑神经细胞上补体 C3 受体的表达水平。然后进行酶联免疫吸附试验（ELISA）检测，检测脑出血外周区脑源性神经营养因子和神经促进因子β的释放量。最后，还测定了大脑神经细胞上补体 C3 受体的表达水平。