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Synergistic association of clioquinol with antifungal drugs against biofilm forms of clinical Fusarium isolates
Mycoses ( IF 4.9 ) Pub Date : 2020-08-23 , DOI: 10.1111/myc.13142
Magda Antunes de Chaves 1 , Thaís Ferreira do Amaral 2 , Natália Monteiro da Silva Rodrigues Coutinho 2 , Taís Fernanda Andrzejewski Kaminski 3 , Mário Lettieri Teixeira 4 , Luís Flavio Souza de Oliveira 5 , Saulo Fernandes de Andrade 1, 2, 3 , Alexandre Meneghello Fuentefria 1, 2, 3
Affiliation  

The influence of biofilm on the complexity of fungal diseases has been reported in recent years, especially in non‐invasive mycoses such as keratitis and onychomycosis. The difficulty in treating cases of fusariosis in the human medical clinic exemplifies this situation, because when Fusarium spp. are present in the form of biofilm, the permeation of antifungal agents is compromised.

中文翻译:

氯碘羟喹与抗真菌药物对临床镰刀菌分离株生物膜形式的协同作用

近年来已经报道了生物膜对真菌疾病复杂性的影响,特别是在角膜炎和甲真菌病等非侵袭性真菌病中。在人类医疗诊所治疗镰刀菌病病例的困难证明了这种情况,因为当镰刀菌属。以生物膜的形式存在,抗真菌剂的渗透受到损害。
更新日期:2020-08-23
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