In this issue, Wu et al. demonstrate the importance of the neglected interferon (IFN)-independent STING signaling axis in mice. They find that although this axis is important for antiviral HSV-1 resistance, it has a pro-cancer role by promoting T cell death.

中文翻译：

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独立于IFN的STING信号传导：敌还是友？

在这个问题上，吴等。证明被忽视的干扰素（IFN）独立的STING信号轴在小鼠中的重要性。他们发现，尽管该轴对抗病毒HSV-1耐药很重要，但它通过促进T细胞死亡而具有促癌作用。