Monoliths with a continuous porous structure are of great interest due to high transfer efficiency and large surface area in environmental and tissue engineering fields. This study demonstrated a facile method to prepare PCL monoliths with hierarchically porous structure by nonsolvent-thermally induced phase separation. A suitable mixed solvent mixture using ethanol as nonsolvent reduced the amount of dioxane and provided PCL monoliths with three levels of structures. The monolith structure was easily controlled by changing the fabrication parameters, such as the nonsolvent, the temperature of phase separation, the concentration of the PCL. Finally, the superhydrophilic monolith was easily obtained by polydopamine surface modification. The easy way of fabrication of a hierarchically porous PCL monolith with superhydrophilicity will find applications such as in tissue engineering and purification.

中文翻译：

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基于非溶剂热诱导相分离的分级多孔超亲水聚己内酯整体的制备

由于在环境和组织工程领域具有高转移效率和大表面积，具有连续多孔结构的整体材料引起了人们的极大兴趣。本研究展示了一种通过非溶剂热诱导相分离制备具有分级多孔结构的 PCL 整体材料的简便方法。使用乙醇作为非溶剂的合适混合溶剂混合物减少了二恶烷的量，并提供了具有三级结构的 PCL 整体。通过改变非溶剂、相分离温度、PCL浓度等制造参数，可以很容易地控制整体结构。最后，通过聚多巴胺表面改性，很容易得到超亲水的整体材料。