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Recommendations for the surveillance of multidrug-resistant bacteria in Italian long-term care facilities by the GLISTer working group of the Italian Association of Clinical Microbiologists (AMCLI).
Antimicrobial Resistance & Infection Control ( IF 5.5 ) Pub Date : 2020-07-13 , DOI: 10.1186/s13756-020-00771-0
Richard Aschbacher 1 , Leonardo Pagani 2 , Roberta Migliavacca 3 , Laura Pagani 3 ,
Affiliation  

Long-term care facilities (LTCFs) are an important reservoir of multidrug-resistant organisms (MDROs). Colonization of LTCF residents by MDROs is generally higher in Italy compared to other European countries. The present review by the working group for the study of infections in LTCFs (GLISTer) of the Italian Association of Clinical Microbiologists (AMCLI) aims to propose criteria for a laboratory-based surveillance of MDROs in Italian LTCFs. We recommend the adhesion to three levels of laboratory-based MDROs surveillance in LTCFs: i) mandatory MDRO surveillance by cumulative retrospective analysis of antimicrobial susceptibility data, obtained as part of routine care of clinical specimens. ii) strongly recommended surveillance by active rectal swab cultures or molecular screening to determine colonization with carbapenemase-producing Enterobacterales, should a resident be proven infected. iii) voluntary surveillance by prospective MDRO surveys, mainly based on point prevalence colonization studies, allowing to determine the MDROs baseline prevalence in the facility. Laboratory-based surveillance of MDROs in LTCFs is aimed at providing useful epidemiological information to healthcare providers operating in the facility, but it is only effective if the collected data are used for infection prevention and control purposes, targeting the peculiar aspects of LTCFs.

中文翻译:

意大利临床微生物学家协会(AMCLI)的GLISTer工作组提出的在意大利长期护理机构中监测耐多药细菌的建议。

长期护理设施(LTCF)是耐多药生物(MDRO)的重要储存库。与其他欧洲国家相比,意大利的MDRO对LTCF居民的殖民化程度通常更高。意大利临床微生物学家协会(AMCLI)的LTCF感染研究工作组(GLISTer)进行的本次审查旨在为意大利LTCF的MDRO实验室监测提出标准。我们建议在LTCF中坚持三个基于实验室的MDRO监测水平:i)通过对抗生素敏感性数据进行累积回顾性分析来进行强制性MDRO监测,作为临床标本常规护理的一部分。ii)强烈建议通过活动的直肠拭子培养进行监视或进行分子筛查,以确定产生碳青霉烯酶的肠杆菌是否定植(如果证明居民已被感染)。iii)通过主要基于点流行率定殖研究的前瞻性MDRO调查进行自愿监视,从而可以确定设施中MDRO的基线流行率。基于实验室的LTCF中MDRO的监视旨在为在该机构中运营的医疗保健提供者提供有用的流行病学信息,但是只有将收集的数据用于LTCF特殊方面的感染预防和控制目的时才有效。可以确定设施中MDRO的基线患病率。基于实验室的LTCF中MDRO的监视旨在为在该机构中运营的医疗保健提供者提供有用的流行病学信息,但是只有将收集的数据用于LTCF特殊方面的感染预防和控制目的时才有效。可以确定设施中MDRO的基线患病率。基于实验室的LTCF中MDRO的监视旨在为在该机构中运营的医疗保健提供者提供有用的流行病学信息,但是只有将收集的数据用于LTCF特殊方面的感染预防和控制目的时才有效。
更新日期:2020-07-13
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