Oilseed brassicas stand as the second most valuable source of vegetable oil and the third most traded one across the globe. However, the yield can be severely affected by infections caused by phytopathogens. White rust is a major oomycete disease of oilseed brassicas resulting in up to 60% yield loss globally. So far, success in the development of oomycete resistant Brassicas through conventional breeding has been limited. Hence, there is an imperative need to blend conventional and frontier biotechnological means to breed for improved crop protection and yield. This review provides a deep insight into the white rust disease and explains the oomycete-plant molecular events with special reference to Albugo candida describing the role of effector molecules, A. candida secretome, and disease response mechanism along with nucleotide-binding leucine-rich repeat receptor (NLR) signaling. Based on these facts, we further discussed the recent progress and future scopes of genomic approaches to transfer white rust resistance in the susceptible varieties of oilseed brassicas, while elucidating the role of resistance and susceptibility genes. Novel genomic technologies have been widely used in crop sustainability by deploying resistance in the host. Enrichment of NLR repertoire, over-expression of R genes, silencing of avirulent and disease susceptibility genes through RNA interference and CRSPR-Cas are technologies which have been successfully applied against pathogen-resistance mechanism. The article provides new insight into Albugo and Brassica genomics which could be useful for producing high yielding and WR resistant oilseed cultivars across the globe.

中文翻译：

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油籽芥菜中宿主-病原体相互作用和抗白锈病策略的基因组和分子视角

油籽芸苔属植物油的第二大最有价值来源，也是全球第三大交易来源。然而，植物病原体引起的感染会严重影响产量。白锈病是油籽芸苔属的主要卵菌病害，导致全球产量损失高达 60%。迄今为止，通过常规育种开发抗卵菌的芸苔属植物的成功有限。因此，迫切需要将传统和前沿生物技术手段结合起来进行育种，以提高作物保护和产量。这篇综述提供了对白锈病的深入了解，并特别参考了 Albugo candida 解释了卵菌-植物分子事件，描述了效应分子的作用，A. candida secretome，和疾病反应机制以及核苷酸结合的富含亮氨酸重复受体 (NLR) 信号。基于这些事实，我们进一步讨论了在油籽芸苔属易感品种中转移白锈病抗性的基因组方法的最新进展和未来范围，同时阐明了抗性和易感基因的作用。通过在宿主中部署抗性，新的基因组技术已被广泛用于作物可持续性。NLR 库的富集、R 基因的过表达、通过 RNA 干扰和 CRSPR-Cas 沉默无毒和疾病易感基因是已成功应用于对抗病原体抗性机制的技术。