Dermatophytosis is a fungal infection of the skin caused by a group of pathogenic fungi known as dermatophytes. Therefore, we investigated those medicinal plants that were being used by local people and traditional healers to treat skin infections in the Mopani District, Limpopo Province. A survey was conducted through the use of a semistructured program to gather information on the common names, plant parts used, methods of preparation, and administration of the medicine. Findings of the survey revealed that over 30 plant species were used for the treatment of skin infections in the area. The most common local mode of medicinal preparation to treat skin was decoction (37%), followed by paste (21%), infusion (19%), poultice (9%), smoke (7%), maceration (5%), and steam (2%). Of the species, only 12 (Ficus sur L., Peltophorum africanum Sond., Vangueria infausta Burch. subsp. infausta, Diospyros mespilliformis Hochst. ex. A. DC., Ziziphus mucronata Willd. subsp. mucronata, Euclea divinorum Hiern, Ximenia caffra Sond., Dombeya rotundifolia Hochst., Ficus sycomorus L., Sideroxylon inerme L. subsp inerme, Parinari curattellifolia Planch. ex Benth., and Maytenus undata (Thunb.) Blakelock) were selected based on literature and ethnobotanical information. We further investigated the antifungal activity of acetone and aqueous extracts of the above mentioned selected plant species using serial dilution assay against Trichophyton rubrum, Microsporum canis, and Candida albicans. All plant extracts were active against the tested microorganisms with minimum inhibitory concentration (MIC) values ranging between 0.02 mg/mL and 1.25 mg/mL. In the bioautography assay, more active compounds were visible in acetone and water extracts of E. divinorum. No active compounds were observed in some plant extracts with excellent antifungal activity, as shown in the microdilution assay. Findings, in general, suggest that the identified plant species, especially those with extracts showing relatively low MIC values, are playing a big role in treating skin infections in Mopani District.

皮肤癣菌病是由一组被称为皮肤真菌的致病真菌引起的皮肤真菌感染。因此，我们调查了林波波省Mopani区当地人和传统治疗师用来治疗皮肤感染的那些药用植物。通过使用半结构化程序进行了一项调查，以收集有关通用名称，使用的植物部位，制备方法和药物管理的信息。调查结果显示，该地区使用了30多种植物来治疗皮肤感染。治疗皮肤的最常见的局部药物治疗方式是水煎（37％），其次是糊剂（21％），输液（19％），药膏（9％），烟尘（7％），浸软（5％），和蒸汽（2％）。在该物种中，只有12（Ficus surL.，Peltophorum africanum Sond。，Vangueria infausta Burch。亚种 Infausta，Diospyros mespilliformis Hochst。例如 A. DC。，Zipziphus mucronata Willd。亚种 mucronata，Euclea致幻Hiern，海檀木属caffra SOND，非洲芙蓉属圆叶赫司特，榕sycomoru小号L.，Sideroxylon inerme L.亚inerme，Parinari curattellifolia猕猴桃。前Benth。和Maytenus undata（Thunb。）Blakelock）是根据文献和民族植物学信息选择的。我们进一步研究的丙酮和使用针对连续稀释测定上述选择的植物物种的水提取物的抗真菌活性红色毛癣菌，犬小孢子菌，和白色念珠菌。所有植物提取物均具有最低0.02 mg / mL至1.25 mg / mL的最低抑菌浓度（MIC）值，对被测微生物具有活性。在生物自显影分析中，E。divinorum的丙酮和水提取物中可见更多的活性化合物。。如微稀释分析所示，在某些植物提取物中未观察到具有优异抗真菌活性的活性化合物。一般而言，研究结果表明，所鉴定的植物物种，特别是那些提取物的MIC值相对较低的植物，在治疗莫帕尼地区的皮肤感染中起着重要作用。