An original synthesis of Ca, Mg, and Zn 2-ethylhexanoate (octoate) obtained by reaction between metallic powder with 2-ethylhexanoic acid was achieved. The activities of obtaining biocompatible catalysts of lactide polymerization were tested. The most active catalyst was zinc 2-ethylhexanoate (ZnOct₂), and the lowest activity catalyst was calcium 2-ethylhexanoate (CaOct₂). The ROP process was successfully optimized by using the design of the experiment. Polylactide with M_w = 82.3 kg/mol with lactide conversion up to 85% and 8% content of D-lactic acid has been obtained. Thus, the obtained polylactides can be used in medical and pharmaceutical devices.

中文翻译：

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丙交酯聚合的生物相容性催化剂-催化剂活性，外消旋作用以及基于实验设计的聚合优化

通过金属粉末与2-乙基己酸的反应获得了Ca，Mg和2-乙基己酸锌（辛酸酯）的原始合成。测试了获得丙交酯聚合的生物相容性催化剂的活性。活性最高的催化剂是2-乙基己酸锌（ZnOct ₂），活性最低的催化剂是2-乙基己酸钙（CaOct ₂）。通过使用实验设计成功地优化了ROP流程。聚丙交酯与中号_瓦特=82.3公斤/摩尔与丙交酯转化高达d乳酸的含量为85％和8％的已被获得。因此，所获得的聚丙交酯可以用于医疗和制药装置。