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Psychological Wellbeing and Aortic Stiffness
Hypertension ( IF 8.3 ) Pub Date : 2020-09-01 , DOI: 10.1161/hypertensionaha.119.14284
Ai Ikeda 1, 2 , Andrew Steptoe 1 , Martin Shipley 1 , Ian B Wilkinson 3 , Carmel M McEniery 3 , Takeshi Tanigawa 2 , Archana Singh-Manoux 1, 4 , Mika Kivimaki 1 , Eric J Brunner 1
Affiliation  

Supplemental Digital Content is available in the text. This study investigated 2 distinct aspects of positive wellbeing: affective wellbeing and eudaimonia with progression of aortic stiffness, an index of subclinical cardiovascular disease. A total of 4754 participants (mean age 65.3 years, 3466 men, and 1288 women) from the Whitehall II cohort study provided data on affective and eudaimonic wellbeing using subscales from the control, autonomy, self-realization and pleasure-19 questionnaire. Aortic stiffness was measured by aortic pulse wave velocity (PWV) at baseline (2008–2009) and 5 years later (2012–2013). Linear mixed models were used to measure the effect of affective and eudaimonic wellbeing on baseline PWV and 5-year PWV longitudinal change. A 1-SD higher eudaimonic wellbeing was associated with lower baseline PWV in men (β=−0.100 m/s [95% CI=−0.169 to −0.032]), independent of social, behavioral, and biological factors. This association persisted over 5 years. No such association was found in women (β=−0.029 m/s [95% CI=−0.126 to 0.069]). We did not find any association of positive wellbeing with change in PWV over time in either men or women. In older men, higher levels of eudaimonic wellbeing were associated with lower long-term levels of arterial stiffness. These findings support the notion that the pattern of association between positive wellbeing and cardiovascular health outcomes involves eudaimonic rather than affective wellbeing and is sex-specific.

中文翻译:

心理健康和主动脉僵硬

文本中提供了补充数字内容。这项研究调查了积极幸福的两个不同方面:情感幸福和伴随主动脉僵硬进展的幸福感,这是亚临床心血管疾病的一个指标。来自 Whitehall II 队列研究的总共 4754 名参与者(平均年龄 65.3 岁,3466 名男性和 1288 名女性)使用来自控制、自主、自我实现和快乐 19 问卷的分量表提供了有关情感和幸福幸福的数据。通过基线(2008-2009)和 5 年后(2012-2013)的主动脉脉搏波速度 (PWV) 测量主动脉硬度。线性混合模型用于测量情感和幸福对基线 PWV 和 5 年 PWV 纵向变化的影响。1-SD 较高的幸福感与男性较低的基线 PWV 相关(β=-0. 100 m/s [95% CI=-0.169 到 -0.032]),与社会、行为和生物学因素无关。这种关联持续了 5 年多。在女性中没有发现这种关联(β=-0.029 m/s [95% CI=-0.126 到 0.069])。我们没有发现男性或女性的积极幸福感与 PWV 随时间的变化有任何关联。在老年男性中,较高水平的幸福感与较低的长期动脉僵硬度水平相关。这些发现支持这样一种观点,即积极的幸福感和心血管健康结果之间的关联模式涉及幸福而不是情感幸福,并且具有性别特异性。我们没有发现男性或女性的积极幸福感与 PWV 随时间的变化有任何关联。在老年男性中,较高水平的幸福感与较低的长期动脉僵硬度水平相关。这些发现支持这样一种观点,即积极的幸福感和心血管健康结果之间的关联模式涉及幸福而不是情感幸福,并且具有性别特异性。我们没有发现男性或女性的积极幸福感与 PWV 随时间的变化有任何关联。在老年男性中,较高水平的幸福感与较低的长期动脉僵硬度水平相关。这些发现支持这样一种观点,即积极的幸福感和心血管健康结果之间的关联模式涉及幸福而不是情感幸福,并且具有性别特异性。
更新日期:2020-09-01
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