Acute renal damage is the most frequent toxic reaction induced by parenteral administration of iodinated contrast media (ICM), leading to a condition named contrast-induced nephropathy (CIN). This pathology was described by Bartels et al. in 1954 and, in most cases, it is transient and does not imply any relevant modifications of renal function. However, it is related to an increase in morbidity and mortality, being considered the third cause of acute renal failure in hospitalized patients.

中文翻译：

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在对含碘造影剂过敏反应的肠外激发试验中预防造影剂肾病的方案

急性肾损伤是胃肠外注射含碘造影剂 (ICM) 引起的最常见的毒性反应，导致称为造影剂肾病 (CIN) 的病症。Bartels 等人描述了这种病理。在 1954 年，在大多数情况下，它是短暂的，并不意味着肾功能的任何相关改变。然而，它与发病率和死亡率的增加有关，被认为是住院患者急性肾功能衰竭的第三大原因。