Potato accumulates large amounts of soluble sugar during cold storage periods. However, a system based understanding of this process is still largely unknown. Here, we compared the dynamic cold-responded transcriptome of genotypes between cold-induced sweetening resistant (CIS-R) and cold-induced sweetening sensitive (CIS-S) in tubers. Comparative transcriptome revealed that activating the pathways of starch degradation, sucrose synthesis and hydrolysis could be common strategies in response to cold in both genotypes. Moreover, the variation in sugar accumulation between genotypes may be due to genetic differences in cold response, which could be mainly explained: CIS-R genotype was active in starch synthesis and attenuated in sucrose hydrolysis by promoting the coordinate expression of a series of genes involved in starch-sugar interconversion. Additionally, transcription factors, the candidate master regulators of starch-sugar interconversion, were discussed. Taken together, this work has provided an avenue for studying the mechanism involved in the regulation of the CIS resistance.

马铃薯在冷藏期间会积累大量可溶性糖。但是，对这个过程的基于系统的理解仍然是未知的。在这里，我们比较了块茎中冷诱导的抗甜味性（CIS-R）和冷诱导的甜味敏感性（CIS-S）之间基因型的动态冷应答转录组。比较转录组揭示了激活淀粉降解，蔗糖合成和水解的途径可能是两种基因型对寒冷反应的常见策略。此外，基因型之间糖积累的差异可能是由于冷反应的遗传差异所致，这可以主要解释为：CIS-R基因型在淀粉合成中很活跃，在蔗糖水解中通过促进一系列相关基因的协调表达而减弱。在淀粉与糖的相互转化中。另外，还讨论了转录因子，即淀粉与糖相互转化的候选主调节剂​​。综上所述，这项工作为研究独联体耐药性调控机制提供了一条途径。