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Synthesis of substituted pyrimidine using ZnFe2O4 nanocatalyst via one pot multi‐component reaction ultrasonic irradiation
Journal of Heterocyclic Chemistry ( IF 2.4 ) Pub Date : 2020-07-11 , DOI: 10.1002/jhet.4048
Pravin Chavan 1 , Sachin Bangale 2 , Dattatraya Pansare 3 , Rohini Shelke 4 , Shivaji Jadhav 5 , Shrikrushna Tupare 6 , Dhanraj Kamble 7 , Megha Rai 8
Affiliation  

A highly efficient, eco‐friendly, recyclable heterogeneous ZnFe2O4 nanocatalyzed synthesis of 2‐amino‐4‐substituted 1,4‐dihydrobenzo[4,5]imidazo[1,2‐a]pyrimidine‐3‐carbonitrile (4a‐j) derivatives via one pot multicomponent reaction of benzimidazole (1), substituted aromatic aldehyde (2a‐j) and malononitrile (3) under ultrasonic irradiations. Significance of this synthetic approach is short reaction time, easy handling, simplicity, efficiency, high yield, and recoverable catalyst.

中文翻译:

一锅多组分反应超声辐照ZnFe2O4纳米催化剂合成取代嘧啶

高效,环保,可回收的异质ZnFe 2 O 4纳米催化合成2-氨基-4-取代的1,4-二氢苯并[4,5]咪唑并[1,2-a]嘧啶-3-腈(4a- j)通过苯并咪唑(1),取代的芳香醛(2a-j)和丙二腈(3)的一锅多组分反应的衍生物。这种合成方法的意义在于反应时间短,易于处理,简单,高效,高收率和可回收的催化剂。
更新日期:2020-09-08
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