Background. Although several studies investigated the relationship between obesity, osteoarthritis, and pain, no study examined the association between obesity and multijoint pain in the lower limbs. The purpose of this study was to address this gap. Method. This cross-sectional study was performed in Riyadh, Saudi Arabia, between March and April 2019. In this study, a total of 4,661 adults aged 45–79 years with or at high risk for knee osteoarthritis were included from the Osteoarthritis Initiative. The persons who had an elevated risk of developing symptoms of knee osteoarthritis during the study were defined as high risk for knee osteoarthritis. According to the body mass index, participants were categorized into three groups: normal weight (n = 1,068), overweight (n = 1,832), and obese (n = 1,761). Logistic regression was used to examine the association between obesity and multisite pain. Results. The odds of multisite pain was associated significantly () by 1.36 times higher with obesity than normal weight, no, or sigle-site pain, even after adjusting for sociodemographic and health variables Conclusion. Obesity is associated with an increased likelihood of multisite pain in the lower limbs. The results enable clinicians to adopt better standards of practice for the prevention and screening of multisite pain in this community.

中文翻译：

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下肢肥胖和多部位疼痛：骨关节炎倡议的数据。

背景。尽管有几项研究调查了肥胖，骨关节炎和疼痛之间的关系，但没有研究检查肥胖与下肢多关节疼痛之间的关系。这项研究的目的是解决这一差距。方法。这项横断面研究于2019年3月至4月之间在沙特阿拉伯的利雅得进行。在这项研究中，“骨关节炎倡议”纳入了4,661名年龄在45-79岁且患有膝骨关节炎或处于高风险中的成年人。在研究期间发生膝部骨关节炎症状的风险较高的人被定义为膝部骨关节炎的高风险。根据体重指数，参与者分为三组：正常体重（n  = 1,068），超重（n  = 1,832）和肥胖（n  = 1,761）。Logistic回归用于检查肥胖与多部位疼痛之间的关系。结果。多部位疼痛的几率显着相关（）即使调整了社会人口统计学和健康变量后，肥胖也比正常体重高出1.36倍，没有或单身疼痛。结论 肥胖与下肢多部位疼痛的可能性增加有关。结果使临床医生可以采用更好的实践标准来预防和筛查该社区的多部位疼痛。