Ischemic brain injuries are common diseases with high morbidity, disability, and mortality rates, which have significant impacts on human health and life. Microglia are resident cells of the central nervous system (CNS). The inflammatory responses mediated by microglia play an important role in the occurrence and development of ischemic brain injuries. This article summarizes the activation, polarization, depletion, and repopulation of microglia after ischemic brain injuries, proposing new treatment strategies for such injuries through the modulation of microglial function.

中文翻译：

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小胶质细胞及其在缺血性脑损伤中的潜在作用：更新。

缺血性脑损伤是具有高发病率，致残率和死亡率的常见疾病，对人类健康和生活产生重大影响。小胶质细胞是中枢神经系统（CNS）的常驻细胞。小胶质细胞介导的炎症反应在缺血性脑损伤的发生和发展中起重要作用。本文总结了缺血性脑损伤后小胶质细胞的活化，极化，耗竭和重新分布，并通过调节小胶质细胞功能提出了针对此类损伤的新治疗策略。