Abstract Mosquito-borne diseases contribute significantly to disease burden, death, poverty, and social debility all over the world. Among these diseases, dengue, malaria and filariasis are most important diseases spread by mosquitoes. In the present work, the methanolic extract of the unripe fruit peel of Persea americana was tested for the larvicidal activity against the third instar larvae of the three mosquito vectors- Aedes aegypti, Culex quinquefasciatus and Anopheles stephensi for 24 h. The methanol extract of peels showed good larvicidal activity against Anopheles stephensi with LC50 and LC90 values of 6.65 and 71.62 ppm, Aedes aegypti with 7.12 and 86.59 ppm followed by Culex quinquefasciatus with 10.78 and 69.39 ppm respectively. The present study revealed that the methanolic extract of unripe fruit peel of Persea americana showed mosquito larvicidal activity in the order Anopheles stephensi followed by Aedes aegypti and Culex quinquefasciatus in the third instar larval stage.

中文翻译：

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鳄梨 (Persea americana Mill.) 未成熟果皮甲醇提取物对埃及伊蚊、Culex quinquefasciatus 和 Anopheles stephensi 的杀蚊活性

摘要 蚊媒疾病对世界各地的疾病负担、死亡、贫困和社会衰弱做出了重大贡献。在这些疾病中，登革热、疟疾和丝虫病是最重要的由蚊子传播的疾病。在目前的工作中，测试了美洲鲈未成熟果皮的甲醇提取物对三种蚊媒——埃及伊蚊、库蚊和史蒂芬斯蚊的三龄幼虫的杀幼虫活性 24 小时。果皮甲醇提取物对斯蒂芬斯按蚊显示出良好的杀幼虫活性，LC50 和 LC90 值为 6.65 和 71.62 ppm，埃及伊蚊为 7.12 和 86.59 ppm，其次是库蚊，分别为 10.78 和 69.39 ppm。