Although the occurrence of antibiotics and antibiotic resistance genes (ARGs) in aquatic environmental has been widely reported, the distribution and variations of these emerging contaminants in the coral reef regions remain unclear. This study investigated the occurrence of these contaminants, and their spatial and seasonal variations in both coral reef regions and non-coral reef regions adjacent to two typical islands in the South China Sea. Eighteen antibiotics and seven ARGs were detected in the surface water with total concentrations ranging from 43.2 to 441 ng/L, and 2.11 × 10⁴ to 8.00 × 10⁶ copies/L, respectively. Erythromycin-H₂O was the most dominant antibiotic in all samples. QnrD was dominant in the dry season, whereas sul1, sul2, and floR were the most abundant in the wet season, indicating obvious seasonal variations. The distribution of ARGs was mainly influenced by changes in salinity caused by anthropogenic activities in wet season.

尽管已经广泛报道了水生环境中抗生素和抗生素抗性基因（ARG）的发生，但这些新兴污染物在珊瑚礁区域的分布和变化仍不清楚。这项研究调查了在南海两个典型岛屿附近的珊瑚礁区域和非珊瑚礁区域中这些污染物的发生及其空间和季节变化。在地表水中检测到18种抗生素和7种ARGs，总浓度分别为43.2至441 ng / L和2.11×10 ⁴至8.00×10 ⁶拷贝/ L。红霉素-H ₂ O是所有样品中最主要的抗生素。在干旱季节，QnrD占主导地位，而sul1，sul2和floR在雨季最丰富，表明明显的季节变化。ARGs的分布主要受湿季人为活动引起的盐度变化的影响。