Artichoke floral stems (AFS) food waste by-products were examined for their phytochemical constituents and their in vitro and in vivo biological activities. Although that the highest total phenol content and total flavonoid content were found in ethyl acetate extract, methanol extract possessed the strongest DPPH and ABTS radical scavenging activity, and showed the highest reducing ferric antioxidant power (FRAP). The anti-acetylcholinesterase activity was higher in butanol extract, whereas the ethyl acetate extract had the highest inhibitory effect on heat-induced protein denaturation. In alloxan-induced diabetic mice, the AFS methanol extract (AFSE) rich in caffeoylquinic acids and flavones reduced blood glucose, alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase, creatinine, and improved liver, and renal antioxidative status. Administration of AFSE to diabetic mice reduced total cholesterol, triglycerides, LDL-cholesterol, and the atherogenic index of plasma (AIP) suggesting its hypolipidemic action. Overall, AFS could be considered as attractive source of health-promoting ingredients.

研究了朝鲜蓟花梗（AFS）食物垃圾副产物的植物化学成分及其体外和体内生物活动。尽管在乙酸乙酯提取物中发现了最高的总酚含量和总黄酮含量，但是甲醇提取物具有最强的DPPH和ABTS自由基清除活性，并显示出最高的还原铁抗氧化能力（FRAP）。丁醇提取物中的抗乙酰胆碱酯酶活性较高，而乙酸乙酯提取物对热诱导的蛋白质变性具有最高的抑制作用。在四氧嘧啶诱导的糖尿病小鼠中，富含咖啡酰奎尼酸和黄酮的AFS甲醇提取物（AFSE）降低血糖，丙氨酸氨基转移酶（ALT），天冬氨酸氨基转移酶（AST），碱性磷酸酶，肌酐，并改善肝脏和肾脏的抗氧化状态。对糖尿病小鼠施用AFSE可降低总胆固醇，甘油三酸酯，LDL-胆固醇，血浆的动脉粥样硬化指数（AIP）表明其具有降血脂作用。总体而言，AFS可以被视为促进健康成分的诱人来源。