The intensity of accumulation and excretion of atrial natriuretic peptide in myocytes of the right atrium in rat models of renovascular hypertension and salt loading was studied by immunocytochemical analysis and transmission electron microscopy. The data suggest that high BP is not the decisive factor affecting secretion of atrial natriuretic peptide in atrial cardiomyocytes. The regulatory mechanisms of the accumulation and release of the peptide from myocyte granules can vary and depend on the pathogenesis of hypertension.

中文翻译：

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实验性高血压患者分泌性心肌细胞心房利钠肽的合成与排泄

通过免疫细胞化学分析和透射电镜研究肾血管性高血压和盐负荷模型大鼠右心房肌细胞中心钠素的蓄积和排泄强度。资料表明，高血压并不是影响心房心肌细胞分泌心钠素的决定性因素。肌细胞颗粒中肽的积累和释放的调节机制可以变化并取决于高血压的发病机制。