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Phytochemical composition and biological activity of Neurada procumbens L. growing in southern Algeria
Journal of Food Processing and Preservation ( IF 2.5 ) Pub Date : 2020-07-09 , DOI: 10.1111/jfpp.14774
Imane Chelalba 1 , Naima Benchikha 1 , Samir Begaa 2 , Mohammed Messaoudi 2 , Hanane Debbeche 1 , Abdelkrim Rebiai 1 , Fadia S. Youssef 3
Affiliation  

Neurada procumbens L. (Neuradaceae) is one of the most popular plants in the province of El‐Oued in south‐eastern Algeria. This study aimed to determine the antioxidant effectiveness of the 80% methanol extract of the aerial parts of the plant via the study of three‐way antioxidant activity namely, 2,2′‐azino‐bis(3‐ethylbenzothiazoline‐6‐sulfonic acid) (ABTS), Catalase activity (CAT), and 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH) radical scavenging capacity assays in addition to examining its inhibitory capacity on the proliferation of hepatic (HepG2) and colon cancer (HCT116) cells. Chemical profiling of the major constituents of its extract was tentatively done using LC‐MS in addition to quantitative determination of phenols, flavonoids, and chemical mineral elements by Inductively coupled plasma‐optical emission spectrometry technique (ICP‐OES).

中文翻译:

阿尔及利亚南部生长的Neurada procumbens L.的植物化学组成和生物学活性

伯拉氏中草药L.(Neuradaceae)是阿尔及利亚东南部El-Oued省最受欢迎的植物之一。这项研究旨在通过三向抗氧化剂活性(2,2'-叠氮基双(3-乙基苯并噻唑啉-6-磺酸)的研究来确定植物地上部分的80%甲醇提取物的抗氧化功效。 (ABTS),过氧化氢酶活性(CAT)和2,2-二苯基-1-吡啶甲基肼基(DPPH)自由基清除能力分析,此外还研究了其对肝(HepG2)和结肠癌细胞(HCT116)细胞增殖的抑制能力。除了使用电感耦合等离子体发射光谱法(ICP-OES)定量测定酚,类黄酮和化学矿物元素外,还尝试使用LC-MS对提取物中主要成分进行化学分析。
更新日期:2020-07-09
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