Abstract In this paper, the microwave-assisted synthesis of carboxymethyl cellulose-cl-poly(lactic acid–co-itaconic acid)/ZnO-Ag nanocomposite [CMC-cl-p(LA-co-IA)/ZnO-Ag] has been discussed. Lactic acid (LA) and itaconic acid (IA) monomers were grafted onto carboxymethyl cellulose (CMC) using potassium persulphate and N, N'-methylene-bis-acrylamide (MBA) as initiator and crosslinker, respectively at optimized conditions of temperature and pressure. The nanocomposite was characterized using different techniques such as Fourier transform infrared spectroscopy (FTIR), field emission scanning electron microscopy (FESEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), thermogravimetric analysis (TGA) and energy dispersive X-ray (EDX). XRD, TEM and FTIR spectral analysis confirmed the formation of the nanocomposite. The release of amoxicillin drug-using nanocomposite as a function of pH and time has been investigated. The maximum drug release of 94.64% was pragmatic at pH 2.2 after 6 h. The degradation of congo red using nanocomposite followed the pseudo-first-order reaction model with the regression coefficient (R2) values of 0.99312. The nanocomposite was also explored for anticancer behavior against yeast cells.

中文翻译：

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羧甲基纤维素-cl-聚(乳酸-共-衣康酸)/ZnO-Ag纳米复合材料的抗癌和光催化活性研究

摘要 本文采用微波辅助合成羧甲基纤维素-cl-聚（乳酸-共-衣康酸）/ZnO-Ag纳米复合材料[CMC-cl-p(LA-co-IA)/ZnO-Ag]进行了讨论。使用过硫酸钾和 N, N'-亚甲基双丙烯酰胺 (MBA) 作为引发剂和交联剂, 在优化的温度和压力条件下, 乳酸 (LA) 和衣康酸 (IA) 单体接枝到羧甲基纤维素 (CMC) 上. 使用不同的技术对纳米复合材料进行表征，例如傅里叶变换红外光谱 (FTIR)、场发射扫描电子显微镜 (FESEM)、透射电子显微镜 (TEM)、X 射线衍射 (XRD)、热重分析 (TGA) 和能量色散 X -射线（EDX）。XRD、TEM 和 FTIR 光谱分析证实了纳米复合材料的形成。已经研究了作为 pH 值和时间函数的阿莫西林药物纳米复合材料的释放。6 小时后，在 pH 2.2 下，94.64% 的最大药物释放是实用的。使用纳米复合材料降解刚果红遵循伪一级反应模型，回归系数 (R2) 值为 0.99312。还探索了纳米复合材料对酵母细胞的抗癌行为。