Background:Klebsiella pneumoniae is currently considered as an immediate threat to human health due to its various multidrug efflux pumps. Microbially synthesized silver nanoparticles (AgNPs) are an attractive and eco-friendly approach to prevent antibiotic resistance in bacteria. In the present study, we compared the inhibitory effect of both commercial and green AgNPs by Bifidobacterium bifidum on OxqAB efflux pump genes in ciprofloxacin-resistant strains of K. pneumoniae.

中文翻译：

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生态友好的生物分子加帽双歧杆菌制造的银纳米颗粒和外排泵基因在肺炎克雷伯菌中的表达改变

背景：肺炎克雷伯菌由于其多种多药外排泵，目前被认为是对人类健康的直接威胁。微生物合成的银纳米粒子 (AgNPs) 是一种有吸引力且环保的方法，可防止细菌对抗生素产生耐药性。在本研究中，我们比较了双歧双歧杆菌的商业和绿色 AgNPs对肺炎克雷伯菌环丙沙星耐药菌株中 OxqAB 外排泵基因的抑制作用。