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ProVision: A web based platform for rapid analysis of proteomics data processed by MaxQuant.
Bioinformatics ( IF 5.8 ) Pub Date : 2020-07-08 , DOI: 10.1093/bioinformatics/btaa620
James Luke Gallant 1, 2 , Tiaan Heunis 1, 3 , Samantha Leigh Sampson 1 , Wilbert Bitter 2, 4
Affiliation  

Proteomics is a powerful tool for protein expression analysis and is becoming more readily available to researchers through core facilities or specialized collaborations. However, one major bottleneck for routine implementation and accessibility of this technology to the wider scientific community is the complexity of data analysis. To this end, we have created ProVision, a free open-source web-based analytics platform that allows users to analyze data from two common proteomics relative quantification workflows, namely label-free and tandem mass tag-based experiments. Furthermore, ProVision allows the freedom to interface with the data analysis pipeline while maintaining a user-friendly environment and providing default parameters for fast statistical and exploratory data analysis. Finally, multiple customizable quality control, differential expression plots as well as enrichments and protein–protein interaction prediction can be generated online in one platform.

中文翻译:

ProVision:一个基于Web的平台,用于快速分析MaxQuant处理的蛋白质组学数据。

蛋白质组学是用于蛋白质表达分析的强大工具,并且通过核心设施或专门的协作,研究人员可以更轻松地使用蛋白质组学。但是,数据实施的复杂性是该技术的常规实施和广泛应用的一个主要瓶颈。为此,我们创建了ProVision,这是一个免费的基于Web的开放源代码分析平台,允许用户分析来自两种常见的蛋白质组学相对定量工作流程的数据,即无标签和基于串联质量标签的实验。此外,ProVision允许自由地与数据分析管道进行交互,同时保持用户友好的环境并提供默认参数,以进行快速的统计和探索性数据分析。最后,进行多个可自定义的质量控制,
更新日期:2020-07-08
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