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Psychological domain of quality of life, depression and anxiety levels in in vitro fertilization/intracytoplasmic sperm injection cycles of women with endometriosis: a prospective study
Journal of Psychosomatic Obstetrics & Gynecology ( IF 3.1 ) Pub Date : 2020-07-08 , DOI: 10.1080/0167482x.2020.1787978
M U Ceran 1 , N Yilmaz 2 , E N Ugurlu 3 , N Erkal 4 , A S Ozgu-Erdinc 2 , Y Tasci 2 , H C Gulerman 2 , Y Engin-Ustun 5
Affiliation  

Abstract

Objective

To evaluate the psychological domain of quality of life (PDQoL), anxiety and depression levels of infertile women with endometriosis versus non endometriosis who applied for Assisted Reproductive Technologies (ART).

Method

This prospective case–control study compromised a total of 105 women who applied for IVF/ICSI program. Ninety-three women were divided into two groups as endometriosis (n = 37) and non-endometriosis (n = 56) after 12 patients who refused to participate in the study were excluded. The WHOQOL-BREF questionnaire, Beck Depression and Anxiety Inventory scales were used to determine the psychological stress levels.

Results

A significant difference was found between the endometriosis and non-endometriosis groups regarding depression scores, while no significant difference was reported with respect to PDQoL and anxiety (p < 0.01, p = 0.897 and p = 0.058, respectively). A weak but significant correlation was observed between depression and endometriosis (CC: 0.435, p < 0.01). Though anxiety scores were found to be higher in endometriosis group this can not reach statistical significance (p = 0.058). Impact of PDQoL, depression and anxiety scores on pregnancy outcomes were found to be insignificant.

Conclusion

Women with endometriosis seem to be more susceptible to depression and anxiety than women without endometriosis. Although infertility treatment outcomes are not found to be significantly affected, the impact of depression and anxiety over ART treatment success merit further research.



中文翻译:

子宫内膜异位症女性体外受精/胞浆内精子注射周期中生活质量、抑郁和焦虑水平的心理领域:一项前瞻性研究

摘要

客观的

评估申请辅助生殖技术 (ART) 的子宫内膜异位症不孕女性与非子宫内膜异位症患者的生活质量心理领域 (PDQoL)、焦虑和抑郁水平。

方法

这项前瞻性病例对照研究共涉及 105 名申请 IVF/ICSI 计划的女性。 排除拒绝参加研究的12名患者后,将93名女性分为子宫内膜异位症(n  = 37)和非子宫内膜异位症(n = 56)两组。WHOQOL-BREF 问卷、贝克抑郁和焦虑量表用于确定心理压力水平。

结果

子宫内膜异位症组和非子宫内膜异位症组在抑郁评分方面存在显着差异,而在 PDQoL 和焦虑方面没有显着差异(分别为p  < 0.01、p  = 0.897 和p  = 0.058)。在抑郁症和子宫内膜异位症之间观察到微弱但显着的相关性(CC:0.435,p  <0.01)。尽管发现子宫内膜异位症组的焦虑评分较高,但这无法达到统计学意义(p  = 0.058)。发现 PDQoL、抑郁和焦虑评分对妊娠结局的影响不显着。

结论

患有子宫内膜异位症的女性似乎比没有子宫内膜异位症的女性更容易患抑郁症和焦虑症。尽管没有发现不孕症治疗结果受到显着影响,但抑郁和焦虑对 ART 治疗成功的影响值得进一步研究。

更新日期:2020-07-08
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