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Do dendritic cells hold the key to regulating cancer antitumor immunity?
Science Translational Medicine ( IF 17.1 ) Pub Date : 2020-07-08 , DOI: 10.1126/scitranslmed.abd3081 Ecaterina Ileana-Dumbrava 1
中文翻译:
树突状细胞是否具有调节癌症抗肿瘤免疫力的关键?
更新日期:2020-07-08
Science Translational Medicine ( IF 17.1 ) Pub Date : 2020-07-08 , DOI: 10.1126/scitranslmed.abd3081 Ecaterina Ileana-Dumbrava 1
Affiliation
PD-L1 blockage on dendritic cells, but not macrophages, may enhance antitumor or CD8+ T cell responses leading to greater tumor growth inhibition.
中文翻译:
树突状细胞是否具有调节癌症抗肿瘤免疫力的关键?
PD-L1对树突状细胞(而非巨噬细胞)的阻滞可增强抗肿瘤或CD8 + T细胞反应,从而导致更大的肿瘤生长抑制作用。