A method for numerical estimation and correction of aberrations of the eye in fundus imaging with optical coherence tomography (OCT) is presented. Aberrations are determined statistically by using the estimate based on likelihood function maximization. The method can be considered as an extension of the phase gradient autofocusing algorithm in synthetic aperture radar imaging to 2D optical aberration correction. The efficacy of the proposed method has been demonstrated in OCT fundus imaging with 6λ aberrations. After correction, single photoreceptors were resolved. It is also shown that wave front distortions with high spatial frequencies can be determined and corrected.

中文翻译：

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通过使似然函数最大化，使用相位梯度自动对焦确定和校正全场光学相干断层扫描中的像差。

提出了一种用光学相干断层扫描（OCT）进行眼底成像中眼睛像差的数值估计和校正的方法。通过使用基于似然函数最大化的估计值来统计确定像差。该方法可以看作是将合成孔径雷达成像中的相位梯度自动聚焦算法扩展到2D光学像差校正的方法。在6个λ像差的OCT眼底成像中已经证明了该方法的有效性。校正后，分离出单个感光体。还显示可以确定和校正具有高空间频率的波阵面畸变。