1‐Benzyl‐1,4‐dihydronicotinamide (BNAH) is a nicotinamide biomimetic reductant effective for generating reduced flavin in the chemo‐enzymatic reaction of bacterial luciferase. This cascade reaction can generate bioluminescence by using common compounds such as long‐chain aldehyde, FMNH‐, and molecular oxygen. The technology developed will be useful for future applications of bacterial luciferase in high‐throughput screening. More information can be found in the full paper by P. Chaiyen et al.

中文翻译：

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封面人物：生物记者应用中细菌荧光素酶的最小化化学级联反应（ChemBioChem 14/2020）

1-苄基-1,4-二氢烟碱酰胺（BNAH）是一种烟酰胺仿生还原剂，可有效减少细菌荧光素酶的化学酶反应中的黄素含量。通过使用常见的化合物（例如长链醛，FMNH-和分子氧），这种级联反应可以产生生物发光。开发的技术将对细菌荧光素酶在高通量筛选中的未来应用有用。有关更多信息，请参见P. Chaiyen等人的全文。