Planarians are a sound, well‐established model system for molecular studies in the field of stem cells, cell differentiation, developmental biology and translational research. Treated stem cell‐less planarians produced by X‐ray treatment are commonly used to study stem cell transcriptional profile and their role in planarian biological processes. X‐ray induces oxidative and DNA damage to differentiated cells, requires expensive radiation machines that are not available in most of the research centres and demand rigorous risk management and dedicated staff.

中文翻译：

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5-氟尿嘧啶处理的涡虫，一种用于研究干细胞异质性和组织老化的多功能模型系统

涡虫是干细胞、细胞分化、发育生物学和转化研究领域分子研究的一个完善、完善的模型系统。通过 X 射线处理产生的经过处理的无干细胞涡虫通常用于研究干细胞转录谱及其在涡虫生物过程中的作用。X 射线会对分化的细胞造成氧化和 DNA 损伤，需要昂贵的辐射机器，大多数研究中心都没有这些机器，并且需要严格的风险管理和专职人员。