Nguyen et al. used transposon sequencing analysis and competitive colonization assays to describe how aspartate/malate can trigger initial Salmonella Typhimurium gut-lumen colonization in mice, providing insight into the significance of certain key metabolites beyond the realm of Salmonella life. Metabolite-driven diagnostic and anti-infective strategies for preventing salmonellosis could rapidly emerge from this work.

中文翻译：

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两种饮食代谢产物可促进沙门氏菌定植。

Nguyen等。使用了转座子测序分析和竞争性定植实验来描述天冬氨酸/苹果酸如何触发小鼠鼠伤寒沙门氏菌肠腔的初始定殖，从而提供了对某些关键代谢产物在沙门氏菌生活领域之外的意义的洞察力。这项工作可以迅速出现由代谢物驱动的诊断和抗感染策略，以预防沙门氏菌病。