We investigated the porcine lymphotropic herpesvirus (PLHV) DNA presence in multiple organs of pigs. Biological samples ( n = 136) included tissue fragments of the central nervous system, heart, kidney, liver, lungs, spleen, urinary bladder, and urine. Sixty-eight (50%) organs were PLHV DNA-positive. None of the urine samples were detected with the virus genome. Although the presence of the PLHV DNA in the urinary bladder and kidney has been detected, it was not possible to show whether urine can be considered an effective route of virus shedding. This study warns to the risk of PLHV zoonotic transmission by xenotransplantation of tissues of porcine origin.

中文翻译：

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巴西猪多个器官中猪嗜淋巴细胞疱疹病毒DNA检测

我们调查了猪的多个器官中存在的猪嗜淋巴细胞疱疹病毒 (PLHV) DNA。生物样本 (n = 136) 包括中枢神经系统、心脏、肾脏、肝脏、肺、脾脏、膀胱和尿液的组织碎片。六十八个 (50%) 器官为 PLHV DNA 阳性。所有尿液样本均未检测到病毒基因组。尽管已检测到膀胱和肾脏中存在 PLHV DNA，但无法证明尿液是否可被视为病毒排出的有效途径。这项研究警告了猪源组织异种移植可能导致 PLHV 人畜共患病传播的风险。