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Surgical outcome of posterior fossa tumours: a Benha experience
Egyptian Journal of Neurosurgery Pub Date : 2020-07-06 , DOI: 10.1186/s41984-020-00083-w
Mohamed Emara , Abd-Elaal Mamdouh , Mohamed M. Elmaghrabi

Posterior fossa brain tumours are one of the most devastating forms of human illnesses which are more common in children. Brainstem compression, herniation and death are the risks with tumours in this critical location. To evaluate our results, complications and outcome of posterior fossa tumour surgery in Benha University Hospital. A prospective study including 44 patients with posterior fossa tumours were performed at the Neurosurgery Department in Benha University Hospital between the period of March 2015 and October 2018. In each case, diagnosis was made clinically and confirmed radiologically and histo-pathologically. Out of 44 patients, 28 (63.6%) patients were males and 16 (36.4%) were females. The mean age was 17.5 + 14.2 years (ranged 2–30 years). This study showed that excellent surgical outcome was observed in 12 cases (27.3%), good in 22 cases (50%) while poor outcome was observed in 10 cases (22.7%). The best outcome is astrocytoma then ependymoma while the worst outcome is metastatic then medulloblastoma which is statistically insignificant. The surgical treatment of posterior fossa tumours still represents a challenge for neurosurgeons. Our Benha experience shows the accepted results, complications and surgical outcome in relation to previous clinical studies. IRB#3747. Registered 18 September 2018.

中文翻译:

后颅窝肿瘤的手术结局:Benha经验

颅后窝颅脑肿瘤是人类疾病中最具破坏性的一种,在儿童中更为常见。脑干受压,疝气和死亡是此关键部位肿瘤的风险。为了评估我们在本哈大学医院进行的颅后窝肿瘤手术的结果,并发症和结局。在2015年3月至2018年10月之间,本哈大学医院神经外科进行了一项前瞻性研究,包括44例后颅窝肿瘤患者。每例病例均进行了临床诊断,并在放射学和组织病理学上得到了证实。在44例患者中,男性28例(63.6%),女性16例(36.4%)。平均年龄为17.5 + 14.2岁(2-30岁)。这项研究表明,有12例(27.3%)观察到了出色的手术结果,22例(50%)良好,而10例(22.7%)不良。最好的结果是星形细胞瘤,然后是室管膜瘤,而最差的结果是转移性的,然后是髓母细胞瘤,这在统计学上是无关紧要的。后颅窝肿瘤的外科手术治疗仍然是神经外科医师的挑战。我们在Benha的经验表明,与先前的临床研究相关的结果,并发症和手术结果均可接受。IRB#3747。2018年9月18日注册。与先前的临床研究相关的并发症和手术结果。IRB#3747。2018年9月18日注册。与先前的临床研究相关的并发症和手术结果。IRB#3747。2018年9月18日注册。
更新日期:2020-07-07
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