Proceedings of the National Academy of Sciences of the United States of America ( IF 11.1 ) Pub Date : 2020-07-21 , DOI: 10.1073/pnas.2001779117 Mohamed A Ghanem 1 , Adam D Maxwell 2, 3 , Yak-Nam Wang 2 , Bryan W Cunitz 2 , Vera A Khokhlova 2, 4 , Oleg A Sapozhnikov 2, 4 , Michael R Bailey 2, 3
In certain medical applications, transmitting an ultrasound beam through the skin to manipulate a solid object within the human body would be beneficial. Such applications include, for example, controlling an ingestible camera or expelling a kidney stone. In this paper, ultrasound beams of specific shapes were designed by numerical modeling and produced using a phased array. These beams were shown to levitate and electronically steer solid objects (3-mm-diameter glass spheres), along preprogrammed paths, in a water bath, and in the urinary bladders of live pigs. Deviation from the intended path was on average <10%. No injury was found on the bladder wall or intervening tissue.
中文翻译:
对生物体内物体的无创声学处理。
在某些医疗应用中,通过皮肤发射超声波束以操纵人体中的固体物体将是有益的。这样的应用包括,例如,控制可摄取的照相机或排出肾结石。在本文中,通过数值建模设计了特定形状的超声波束,并使用相控阵产生了超声波束。这些光束显示出可以沿预定路径,在水浴中以及在生猪的膀胱中悬浮并以电子方式操纵固体物体(直径3毫米的玻璃球)。与预期路径的偏差平均<10%。在膀胱壁或介入组织上未发现损伤。