The WHO has declared coronavirus disease‐2019 (COVID‐19) outbreak as a global pandemic.1 The outbreak of COVID‐19 caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has spread in 213 countries across the world. As of 30 June 2020, the total confirmed cases of COVID‐19 have reached over 11 million with over half million deaths globally.2 During the COVID‐19 pandemic, dengue cases have been increased in most of the dengue‐endemic countries in the world. While COVID‐19 causes havoc across the world, countries in South and South‐East Asia and Latin America are faced with the prospect of a second epidemic: dengue.3 The countries in South America like Brazil, Paraguay, Bolivia, Argentina, Colombia, Mexico, and in the Southeast Asia like the Philippines, Malaysia, Singapore, Vietnam, Thailand, and Indonesia are currently in the high risk of dengue outbreak as dengue infection is increasing at an alarming rate.4, 5 Besides, several South Asian countries like India, Pakistan, and Bangladesh are also suffering from dengue disease this year. Interestingly, almost all these countries are currently suffering seriously from COVID‐19 due to its pandemic situation.4 Therefore, in these countries both COVID‐19 and dengue are occurring simultaneously.

Dengue, a mosquito‐borne viral infection, itself a great threat in the world. Severe dengue is a leading cause of serious illness and death in some Asian and South American countries that are dengue endemic.6 The dengue‐endemic countries have a history of occurring repeated outbreak of dengue. During the COVID‐19 crisis, the situation would be very difficult to manage if the dengue epidemic is further added in these countries. At present all the countries are struggling against COVID‐19, further epidemic of dengue will really pose new challenges to combat. As the combination of COVID‐19 and dengue is assumed as dangerous for health care professionals in any country.

Corona and dengue, both viruses are coexisting currently in the dengue‐endemic countries. Therefore, the coinfection of these viruses to the patients has been reported recently in different dengue‐endemic countries like Singapore, Thailand, India, and Bangladesh. As an extremely unique occurrence, Singapore at first confirmed two patients who were coinfected with both corona and dengue virus.7 In Thailand, a man who also had dengue died from coronavirus infection.8 Also, an old patient with coinfection of dengue and corona died in India.9 Moreover, two patients from Bangladesh were coinfected with both corona and dengue and one of them died.10 Hence, it can be speculated that coinfection cases may be increased in the upcoming days as peak dengue season. Coinfection poses a challenge for accurate diagnosis and treatment, particularly when symptoms such as fever and aches are similar for several viral diseases like COVID‐19 and dengue. The distinction can be made with disease progresses. In fact, the symptoms of these viral diseases begin with fever. Guan et al11 in their recent study reported that fever, cough, and headache were observed as the most common symptoms for patients with COVID‐1911 whereas fever, headache, and skin rash were observed for patients with dengue. Besides, patient with COVID‐19 could present with a rash that was mistaken for dengue.8 The clinical and laboratory features of both dengue and COVID‐19 are quite identical, and therefore, it is difficult to distinguish. In Singapore, patient with COVID‐19 produced false‐positive dengue results in rapid serological test.7 Thus, a new symptom of COVID‐19 was discovered where the patient was suspected of suffering from dengue. The report warned that patients with COVID‐19 were wrongly considered as dengue resulting a delay in diagnosis of corona infection and further spread of the virus.7

The dengue‐endemic countries are at the risk of possible coinfection and coepidemics in where COVID‐19 and dengue disease are coexisting, and the viruses are cocirculating. It has appeared that several patients have been coinfected with corona and dengue virus and coepidemics have also been started in several countries. Coinfections may cause illness with overlapping signs and symptoms that make diagnosis and treatment difficult for physicians. Coepidemics of dengue and COVID‐19 have been grown as a new burden. Thus, coinfection and coepidemics trigger alert, especially in the dengue‐endemic countries where the dengue epidemic occurred repeatedly. For facing the upcoming dengue epidemic, special measures should be taken in these countries and therefore, an effective mosquito control program is strongly recommended.

世界卫生组织已宣布冠状病毒病-2019 (COVID-19) 爆发为全球大流行。1由严重急性呼吸综合征冠状病毒 2 (SARS-CoV-2) 引起的 COVID-19 疫情已在全球 213 个国家蔓延。截至 2020 年 6 月 30 日，全球 COVID-19 确诊病例总数已超过 1100 万，死亡人数超过 50 万。2在 COVID-19 大流行期间，世界上大多数登革热流行国家的登革热病例有所增加。尽管 COVID-19 在全球范围内造成严重破坏，但南亚、东南亚和拉丁美洲国家面临着第二次流行病的前景：登革热。3巴西、巴拉圭、玻利维亚、阿根廷、哥伦比亚、墨西哥等南美洲国家和菲律宾、马来西亚、新加坡、越南、泰国和印度尼西亚等东南亚国家目前处于登革热爆发的高风险中，因为登革热感染正在以惊人的速度增长。4, 5此外，印度、巴基斯坦、孟加拉国等几个南亚国家今年也出现登革热。有趣的是，由于 COVID-19 的大流行，几乎所有这些国家目前都在遭受严重的痛苦。4因此，在这些国家，COVID-19 和登革热同时发生。

登革热是一种由蚊子传播的病毒感染，它本身就是对世界的巨大威胁。在一些登革热流行的亚洲和南美国家，重症登革热是导致严重疾病和死亡的主要原因。6登革热流行国家有多次发生登革热疫情的历史。在 COVID-19 危机期间，如果这些国家进一步增加登革热疫情，情况将非常难以管理。目前各国都在与COVID-19作斗争，登革热的进一步流行确实会给抗击带来新的挑战。由于 COVID-19 和登革热的结合被认为对任何国家的医疗保健专业人员都是危险的。

冠状病毒和登革热这两种病毒目前在登革热流行国家共存。因此，最近在新加坡、泰国、印度和孟加拉国等不同的登革热流行国家报告了这些病毒对患者的共同感染。作为一个极其独特的事件，新加坡首先确认了两名同时感染了冠状病毒和登革热病毒的患者。7在泰国，一名也患有登革热的男子死于冠状病毒感染。8此外，一名同时感染登革热和冠状病毒的老年患者在印度死亡。9此外，来自孟加拉国的两名患者同时感染了新冠病毒和登革热，其中一人死亡。10因此，可以推测，随着登革热高峰期的到来，未来几天内共感染病例可能会增加。合并感染对准确诊断和治疗提出了挑战，特别是当发烧和疼痛等症状与 COVID-19 和登革热等几种病毒性疾病相似时。可以根据疾病进展进行区分。事实上，这些病毒性疾病的症状始于发烧。Guan 等人11在他们最近的研究中报告说，发烧、咳嗽和头痛是 COVID-19 患者最常见的症状11，而登革热患者则观察到发烧、头痛和皮疹。此外，COVID-19 患者可能会出现被误认为登革热的皮疹。8登革热和 COVID-19 的临床和实验室特征非常相似，因此难以区分。在新加坡，COVID-19 患者在快速血清学检测中出现了假阳性登革热结果。7因此，在疑似患有登革热的患者中发现了一种新的 COVID-19 症状。该报告警告说，COVID-19 患者被错误地认为是登革热，导致延误诊断冠状病毒感染并进一步传播病毒。7

在 COVID-19 和登革热疾病并存且病毒在共同传播的情况下，登革热流行国家面临可能同时感染和共同流行病的风险。似乎有几名患者同时感染了冠状病毒和登革热病毒，并且在几个国家也开始出现共同流行病。合并感染可能导致症状和体征重叠的疾病，使医生难以诊断和治疗。登革热和 COVID-19 的共同流行已成为一种新的负担。因此，合并感染和共同流行病会引发警报，尤其是在登革热流行反复发生的登革热流行国家。面对即将到来的登革热疫情，这些国家应采取特殊措施，因此强烈建议采取有效的蚊虫控制计划。